This line was established in 1992 by kathryn a.
Lung cell line mouse.
Cmt 167 was isolated by subcloning and in vivo screening for high metastatic potential.
Immune checkpoint inhibitors targeting the interaction between programmed cell death 1 pd 1 and its ligand pd l1 induce tumor regression in a subset of non small cell lung cancer patients.
I found that wi38 is a human lung fibroblast line not from mouse.
Cultures were established from malignant mesothelial cells obtained from ascites fluid.
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It is not known how dome formation in line 3041 would respond to these sodium channel inhibitors or to ecm components or whether this cell line is unique among mouse lung epithelial cell lines in displaying this differentiated property.
It is mentioned in the article you attached and also in the sigma aldrich website from where i wanted to get it.
Wikenheiser from pulmonary tumors in a mouse transgenic for the sv40 large t antigen under the control of the promoter region of the human surfactant protein c gene.
However clinical response rates are less than 25.
The purpose of choosing a particular type of tissue is for disease or protein assessment or retroviral vector production and cell culture support.
Cell line origin mouse malignant mesothelioma cell line description mice balb c female 6 8 weeks were exposed to crocidolite asbestos through intraperitoneal injection resulting in tumour development.
Evaluation of combinations of immunotherapy with existing.
Metastasis cmt 167 is a highly metastatic subclone of murine alveogenic lung carcinoma cell line cmt 64 ecacc catalogue number 10032301.
Top 5 design considerations for preclinical immuno oncology studies top 5 models for immuno oncology studies.
Line 3041 then represents a useful tool for studying the regulation of alveolar fluid regulation.